This note discusses, through selected country case studies, how digital health records and telemedicine can improve delivery quality, access to underserved populations, and resource utilization in healthcare. In addition, it shows how digital disease surveillance tools can identify outbreaks and track the spread of diseases, while novel digital platforms can facilitate patent licensing and international pooled procurements for better drug access in developing countries. Ensuring safe and well-regulated collection and use of healthcare data, as well as facilitating standardization and interoperability of digital infrastructure in different sectors is critical for the success of these interventions.