This paper presents Ghana’s Poverty Reduction and Growth Strategy. The vision of the Agenda For Jobs II (2022–2025) is to create an optimistic, self-confident and prosperous nation, through the creative exploitation of our human and natural resources, and operating within a democratic, open and fair society in which mutual trust and economic opportunities exist for all. The Services sector continues to contribute the highest share of gross domestic product (GDP) despite its decline and varied performance of 47.9 percent in 2020, 48.2 percent in 2019 and 47.0 percent in 2018. Industry’s share of GDP decreased from 33.5 percent in 2018 to 33.2 percent in 2019 and 31.6 percent in 2020. Agriculture’s contribution to GDP increased to 20.5 percent in 2020 from 19.5 percent in 2018 and 18.5 percent in 2019. Key challenges requiring attention include the proliferation of slums due to increased rural–urban migration; poor sanitation and noise pollution; weak enforcement of environmental and mining laws and regulations leading to increased illegal mining, forest degradation and water pollution.